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- <text id=89TT3108>
- <title>
- Nov. 27, 1989: Brain Defender
- </title>
- <history>
- TIME--The Weekly Newsmagazine--1989
- Nov. 27, 1989 Art And Money
- </history>
- <article>
- <source>Time Magazine</source>
- <hdr>
- MEDICINE, Page 56
- Brain Defender
- </hdr><body>
- <p>A new drug slows the progress of Parkinson's disease
- </p>
- <p> Among the greatest terrors of old age is the fear of
- becoming physically crippled. About 600,000 Americans are
- afflicted with Parkinson's disease, which is marked by a
- progressive dying off of the brain cells that control voluntary
- movement. Victims suffer from the shakes, muscle stiffness and
- poor balance; eventually, many become totally disabled. Standard
- treatment for Parkinson's has relied on giving patients
- levodopa. But the drug, which supplies remaining brain cells
- with a vital chemical, simply tempers the disease's symptoms
- without affecting its progress. Even worse, the medication soon
- becomes ineffective. For that reason, doctors wait as long as
- possible after the disease is diagnosed before prescribing
- levodopa.
- </p>
- <p> Now, though, a new drug called deprenyl may represent a
- turning point in therapy for Parkinson's. Deprenyl's
- distinction: it actually slows the progress of the illness. In
- fact, it is the first medication ever to retard a chronic brain
- disorder. Deprenyl or similar drugs could conceivably lead to
- advances in the treatment of other neurological diseases,
- including Alzheimer's.
- </p>
- <p> Researchers reported the conclusive proof of deprenyl's
- effect on Parkinson's in last week's New England Journal of
- Medicine. In a study at 28 U.S. and Canadian medical centers
- involving 800 patients, investigators found that those given
- deprenyl took significantly more time to reach the point where
- they needed levodopa than did those not receiving the drug.
- Based on the results, the researchers project that patients on
- deprenyl can wait twice as long -- about a year -- before taking
- levodopa.
- </p>
-
- </body></article>
- </text>
-
-